Описан в 1937 году турецким дерматологом Hulusi Behçet

International Study Group for Behçet’s Disease Criteria (1989)

Diagnosis requires:  Recurrent oral ulceration: minor aphthous, major aphthous, or herpetiform ulceration observed by physician or by a reliable patient, with recurrence of 3 episodes in one I 2-month period

PLUS > 2/4 of the following: 

I. Recurrent genital ulceration: 

• aphthous ulceration or scarring, observed by physician or by a reliable patient 

2. Eye lesions: 

• anterior uveitis, or 
• posterior uveits or 
• cells in vitreous on slit lamp examination or 
• retinal vasculitis observed by an ophthalmologist 

3. Skin lesions: 

• erythema nodosum, observed by physician or by a reliable patient or 
• pseudofolliculitis, or 
• papulopustular lesions; or 
• acneiform nodules, observed by physician in post-adolescent patients not receiving corticosteroids 

4. Positive pathergy test read by a physician at 24-48 hours: 

• an indurated erythematous papulc or pustule that is> 2mm at the prick site after the application of a sterile needle or intradermal injection of saline 

N.B.  Findings applicable only in absence of other clinical explanations.

O’Duffy Behçet’s Disease Criteria (I974)

Diagnosis requires:  Recurrent oral aphthous ulcers PLUS 2 of: 

• Aphthous genital ulceration 
• Uveitis 
• Cutaneous “pustular” vasculitis 
• Synovitis 
• Meningoencephalitis 

Incomplete form: Recurrent oral aphthous ulcers PLUS > 1 of above criteria  Exclusions:herpes simplex infection, inflammatory bowel disease, Reiter’s syndrome and systemic lupus erythematosus (SLE)

Behçet’s Disease Research Committee of Japan Criteria (I972)

Diagnosis requires: All 4-Major Criteria

Major Criteria:

1. Recurrent aphthous ulceration in the mouth  2. Skin lesions 

• Erythema nodosum-ilke eruptions 
• Subcutaneous thromhophlebitis 
• Hyperirritability of the skin 

3. Eye lesions 

• Recurrent hypopyon iritis or iridocyclitis 
• Chorioretinitis 

4. Genital ulcerations  Incomplete type: 3/4 major criteria, or Recurrent hypopyon-iritis or typical chorioretinitis +1 other major criterion

Minor Criteria:

(Any number may present) 

• Arthritis symptoms (arthralgia, swelling, erythema) 
• Gastrointestinal lesions (e.g appen(licitis-like pains, melena) 
• Epididymitis 
• Vascular lesions (occlusion of blood vessels, aneurysms) 
• Central nervous system involvement 
• Brain stem syndrome 
• Meningo-encephalomyelitic syndrome 
• Confusional type